What causes Interstitial Cystitis?

The exact cause of Interstitial Cystitis (IC) is not fully understood. However, several theories have been proposed, and it is likely that multiple factors may contribute to the development of the condition.

Some of the theories that have been proposed include:

• Autoimmune disorder: Some researchers believe that IC may be caused by an immune system disorder, in which the immune system mistakenly attacks the cells that line the bladder, leading to inflammation and pain.
• Bladder or pelvic trauma: Some researchers believe that IC may be caused by past injury or trauma to the bladder or pelvic area.
• A defect in the bladder's protective lining: Some researchers believe that IC may be caused by a defect or deficiency in the bladder's protective lining, which allows irritants in the urine to cause inflammation and pain.
• Nervous system dysfunction: Some researchers believe that IC may be caused by an abnormal function of the nerves that control the bladder, leading to chronic pain and discomfort.
• Genetics: Some researchers believe that IC may have a genetic component, as some people may have a family history of the condition.
• Hormonal imbalance: Some researchers believe that IC may be caused by an imbalance in hormones such as estrogen and progesterone.

It's worth noting that the exact cause of IC is still not fully understood and it may be a combination of multiple factors. Also, it's important to note that IC is a chronic condition and there is no definitive cure for IC, but various treatments can help to manage the symptoms.