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Heavy Metal Toxicity Testing Overview:

In order to gauge your current state of health, our clinic will often request copies of your last two years of medical testing and will often recommend further testing as needed.  Our clinic does request some testing that is and not commonly performed in more "mainstream" medical clinics.  24-hour heavy metal testing with provoking agent, neurotransmitter analysis, food sensitivity testing, comprehensive stool testing and Candida antigen testing are commonly recommended by our medical staff.   Some of these are discussed in detail in the links in this section.

What to Expect on Your First Visit:

First office visits typically last 45-60 minutes.  Your doctor will review your intake form with you and gather a detailed medical history.  A partial physical exam is usually performed and medical records are often requested from your primary care physician and/or other doctors.  Specialty laboratory testing may be recommended.  Most clients are offered an initial protocol consisting of nutritional supplementation, dietary and life style recommendations.

First Visit: Blood Test

To assess and identify kidney, liver, blood sugar and other key factors such as blood cholesterols. The results are explained to the patient, giving him/her a fuller understanding of the blood chemistry, so that they may take control.

Patients are required to fast for 14 hours before the test. Water may be drunk freely, but not tea, coffee, juices or other beverages. Appointments are normally arranged for mid-morning so that food and drink can be consumed up to 8pm the previous evening. On the day of the appointment, any prescribed medication should be taken with water as normal.

Patients are recommended to bring food to eat after the blood sample has been taken. Diabetics should advise the clinic, and separate arrangements will be made.

First Visit: Urine Analysis

To establish exactly how the kidneys are functioning. Patients are required to collect urine over a period of 24 hours. This should be as near the date of the blood test as possible, but must not include the 14 hours fasting period prior to the appointment.

A recommended timetable is that the first urine of the day should be excluded, than all subsequent urine for the next 24 hours collected in clean plastic containers. (If collection starts at 8am, this process must be followed until 8am the following day.) Eg. Appointment 10am Friday, fasting commences Thursday 8pm. Urine collection starts Wednesday 8am. until Thursday 8am.

Containers should be clearly labeled with the patient’s names and brought to the clinic at the time of their appointment.

First Visit: Resting ECG for Doctors Report

The electrocardiograph (ECG) determines the condition of the heart and measures its actions and the pulse.

The doctor in charge reports any findings in his medical notes.

Specific Heavy Metal Toxicity Testing:

A. Urine Analysis

            What is a Urine Analysis (Urinalysis)?

A Urine Analysis is a series of tests that screens and evaluates the urine sample for abnormalities, presence of various compounds (protein, glucose, ketones), and to check for kidney and metabolic processes. The urinalysis also involves tests that assess the color, appearance, odor, and pH, and blood.

Indications and Contraindications

A urinalysis is a part of routine medical examinations. It is especially done in patients who are pregnant, who are experiencing abdominal pains, blood in urine, frequent or painful urination, symptoms of dysuria, hematuria, diabetes, chronic renal failure, urinary tract infections, and other metabolic diseases.

How do you prepare for a urinalysis?

There is no special diet or preparation before testing. However, let your physician know if you are taking medications as some drugs can alter urinalysis results.

How does it feel? How long does it take?

Collection of urine sample during urinalysis is simple and will not cause you any discomfort. You will be given a container to collect 3-4 ounces of urine. This will only take a few minutes.

Expected effects after the test

There are no risks and side effects after this test.

Special instructions after the test

Practice good hygiene when collecting your urine sample. Wash your hands with soap and water at all times

Interpretation of Results:

Normal Findings

Test

 Normal level/range

Interpretation

Appearance

Color

Clear

Amber yellow

Cloudiness may indicate presence of pus, or bacteria

Red or brown urine indicates blood in the urine (bleeding from kidneys). Green may indicate infection

Odor

Aromatic

Strong smell of acetone indicates diabetic ketoacidosis. Foul odor is indicates presence of UTI. Fecal odor indicates enterovesicle fistula

pH

4.6-8.0

Abnormal pH may indicate kidney or urinary tract disorder. Increased levels indicate alkalemia, UTI. Decreased levels indicate academia, diabetes mellitus, COPD

Protein

0-8 mg/dl, 50-80 mg/24 (at rest), <250 mg/24 hr (during exercise)

Increased levels indicates renal disease, lupus erythematosus, heavy metal poisoning, CHF

Specific gravity

1.005-1.030

Low values indicates renal disease, overhydration, diabetes insipidus, diuresis. High levels indicate dehydration, diarrhea, decreased renal blood flow.

Leukocyte esterase

Negative

Detection of leukocyte esterase indicates possible urinary tract infection

Nitrites

None

Detection of nitrites indicates possible urinary tract infection

Ketones

None

Detection indicates anorexia, hyperthyroidism, diabetes mellitus, aspirin ingestion

Bilirubin

None

Detection indicates gallstones, liver metastasis, Rotor’s syndrome, tumor, inflammation

Urobilinogen

0.01-1.0 Ehrlich units/ml

Increased levels indicate hemolytic anemia, pernicious anemia, hematoma, ecchymosis. Decreased levels indicate cholestasis, biliary obstruction

Crystals

None

Detection indicates renal stone formation, urinary tract infection

Casts

None

Detection indicates UTI, pyelonephritis, acute tubular necrosis, chronic lead poisoning, mercury poisoning, heavy metal poisoning, eclampsia, CHF

Glucose

None

Detection and increased level of glucose indicates kidney damage, diabetes, pregnancy

WBC

0-4 per low power field

Increased WBC indicates bacterial infection.

RBC

≤ 2

Increased RBC indicates primary renal disease, cystitis, prostatitis, bladder trauma.

RBC casts

none

Increased RBC cast indicates systemic lupus erythematosus, vasculitis, subacute bacterial endocarditis

Notes:

Factors such as prolonged refrigeration, presence of sperm in the urethra, consumption of foods such as carrots and beets and some drugs can affect the appearance and odor of the urine sample.

Vaginal discharge can contaminate the urine sample and alter the results.

B. Post Provocation Urine Element Testing

What is the Post Provocation Urine Element Testing?

For diagnosis of the presence of certain toxic element burdens, post provocation testing is recommended.  This involves urine collection following oral or intravenous administration of chelating or complexing agents that mobilize elements from otherwise slowly exchanging tissue pools. For example, non-provoked levels of cadmium, mercury, and lead may not be indicative of deep tissue stores and only reflect ongoing or very recent exposure.

Unprovoked urinary levels of essential elements such as magnesium, calcium, sodium, and potassium may be indicative of renal wasting conditions and provide early warning of renal dysfunction. Magnesium loading tests can also be performed using urine elements testing.    Provoked urinary levels of elements that chelation agents have an affinity for can provide valuable information as to the efficacy of the provocation. Blood levels are better indicators of nutritional element status.

Indications and Contraindications

Analysis of elements in urine provides diagnostic information on potentially toxic elements such as lead, mercury, cadmium, nickel, beryllium, arsenic and aluminum, and assessment of the efficiency of renal reabsorption of essential elements such as magnesium, calcium, sodium and potassium.

Urine element analysis is an invaluable tool for the diagnosis or confirmation of toxic element burden and monitoring of detoxification therapy.

How do you prepare for the Post Provocation Urine Element Testing?

It is recommended to do this test early in the morning as soon as you wake up. Completely empty the bladder before doing this test. Do not eat 1 hour prior to the testing. You may only drink a few amounts of water. Avoid taking vitamin and mineral supplements for more accurate results

How does it feel? How long will it take?

The chelating agents (Captomer) may be administered orally to provoke urinary levels of elements. If administered intravenously, you may feel nothing at all from the needle while chelating agents are being given or you may feel a quick sting or pinch depending on your sensitivity to pain. Administration of chelating agents will only last for a few minutes. However, collection of the urine sample will be done over the next six to 24 hours depending on your physician’s recommendations.

Expected effects after the test:

This test is painless and simple. Normally, you will not feel any side effects after the test.

Special instructions after the test:

If chelating agents were administered intravenously, cover the needle site with a bandage and apply pressure on it for several minutes. If the site becomes swollen, do warm compresses few times a day.

For the next six hours, you may only drink 0.5-1.5 liters of water. You may only eat one hour after administration of chelating agents.

You will be given a container that will be used for collecting your urine sample over the next six to 24 hours. Follow instructions given to you on how to seal and transport the urine sample. Be careful not to contaminate the urine sample.

Practice good hygiene when collecting your urine sample. Wash your hands with soap and water at all times.

You may resume your regular diet after urine sample collection.

Interpretation of Results:

Results of a test are usually available in 10-12 days

Metals

Normal levels

Arsenic

≤50 µg/L

Cobalt

0.1-2.2 µg/L

Copper

25 µg/24 h

Iron

<300 µg/dL

Lead

≤70 µ/dL

Mercury

20 µg/L

Nickel

≤500 µg/L

Silver

2.6 µg/L

Thallium

<3 µg/L

Notes:

Contamination during urine sample collection may alter the results for heavy metals. Specimen should immediately be transported to the laboratory for accuracy or refrigerated if it cannot be processed right away.

Positive results for heavy metal test must be confirmed by repeating the procedure.

The Right Diagnosis and Treatment for Heavy Metal Toxicity

Once the comprehensive review is completed for each patient, our doctors and our team of medical professionals will evaluate your diagnosis. At this point, our doctors will spend one on one time with you to interpret and explain your results. Together you will explore your goals and discuss your treatment plan options. These treatment plans can be implemented using multiple modalities such as medications, hormones, diet, supplements, behavior and lifestyle changes, and alternative therapies. Our doctors will prescribe a preventative and comprehensive treatment plan that is tailored to your needs and fits into your lifestyle.

Patients Medical’s Personal Approach to Heavy Metal Toxicity

Our doctors and our team at Patients Medical will regularly monitor your progress and track the effectiveness of your program making adjustments if necessary. Our goal is to support you and advise you every step of the way.

We work in conjunction with your existing doctors. Any gaps between specialists are filled to ensure we support your overall health and well-being. While we treat serious medical conditions such as Alzheimer’s, Diabetes, Parkinson’s, Multiple Sclerosis, anxiety, depression, and heart disease; the primary objective of our staff is prevention and early detection of disease.