NYC’s Leading Integrative Health Care Center

Anti-Aging and Longevity Treatments Remember when you were in college and stayed up all night drinking beer, eating pizza, and partying; yet you still were able to attend class in the morning? How many of you could do that now?
Bioidentical Hormone Pellet Therapy is an advanced integrative treatment that uses plant-derived hormones identical to those produced by the human body to restore hormonal balance in women experiencing symptoms of menopause, perimenopause, PMS, or hormonal decline. This therapy involves the gentle insertion of tiny hormone pellets under the skin, which release consistent, physiologic doses of estrogen and/or testosterone over several months.
At Patients Medical in NYC, hormone pellet therapy is guided by physician-led testing and personalized dosing to help improve energy, mood, sleep, libido, mental clarity, metabolism, and overall quality of life—addressing the root causes of hormonal imbalance rather than masking symptoms.
Subcutaneous bioidentical hormone pellets that release steady hormone levels for 3–5 months
Improved energy, mood stability, better sleep, increased libido, reduced hot flashes, mental clarity
Restores physiologic hormone levels → stabilizes endocrine signaling
Perimenopause, menopause, PMS, low estrogen or testosterone, hormonal fatigue, mood swings
Works well with nutrition, lifestyle medicine, thyroid care, gut health & functional medicine
Schedule a Hormone Consultation & Lab Testing
Complete a Comprehensive Female Hormone Panel
Begin Personalized Pellet Therapy Program
Track symptom improvement over 8–12 weeks
Maintain results with follow-up monitoring
At Patients Medical, we are a physician-led integrative medical clinic in New York City specializing in hormonal health, women’s wellness, and longevity medicine. For over 40 years, our team has helped women regain hormonal balance using evidence-based bioidentical hormone therapy combined with functional diagnostics and personalized care.
Our philosophy is simple: treat the cause, not just the symptoms.
Established: 1974
Location: Midtown Manhattan
Specialties: Integrative medicine, BHRT, functional endocrinology, women’s health
Team: MDs, DOs, hormone specialists, nutritionists
Care Model: Root-cause diagnostics + personalized hormone optimization
Focus Areas: Menopause, perimenopause, PMS, fatigue, libido, metabolic health
• Thyroid-hormone interactions
• Adrenal fatigue
• Insulin resistance
• Mood & cognitive decline
We view hormonal imbalance as a system-wide issue involving:
Hormones regulate everything from your energy and weight to mood, libido, and brain function. Yet most women facing menopause, fatigue, or PMS are given a one-size-fits-all patch or pill. At Patients Medical in New York City, we use Bioidentical Hormone Replacement Therapy (BHRT) via pellets to restore hormonal balance with precision. Our approach supports you naturally—by testing first, treating gently, and personalizing care throughout your journey.
What Are Bioidentical Hormone Pellets?
Bioidentical hormones are derived from plants and chemically match the hormones your body naturally makes. In pellet therapy, small hormone pellets (testosterone or estrogen) are inserted under the skin and release hormones continuously over 3–6 months. Unlike pills or patches, pellets provide steady dosing, reducing mood swings, energy crashes, or forgotten doses—especially beneficial for women in perimenopause, menopause, or post-hysterectomy stages.
If you’re dealing with the following symptoms, you may benefit from BHRT:
Functional medicine digs deeper than symptom management. We identify why your hormone pathways are out of sync. Common root causes include:
Pellet therapy involves placing custom-compounded hormones (like estrogen or testosterone) under the skin in a quick in-office procedure. Once inserted, the pellets release hormones consistently over several months, mimicking your body’s natural rhythm. This eliminates hormone fluctuations, supports mood stability, and reduces symptoms like fatigue, night sweats, and low libido—all without the hassle of daily creams or pills.
No two women have the same hormone profile. We design treatment plans that may include BHRT pellets, herbal adaptogens, thyroid optimization, and detox support. Your program is guided by lab results and adjusted over time to keep your hormones in balance. This custom approach addresses estrogen dominance, progesterone deficiency, and testosterone decline—helping restore energy, confidence, and cycle control.
We offer IV nutrient infusions to correct deficiencies that impair hormone production and detoxification. Common blends include B-complex for energy, magnesium for stress relief, and glutathione for estrogen clearance. These nutrients support hormone metabolism in the liver, reduce PMS severity, and combat adrenal fatigue—making pellet therapy even more effective when combined with nutrient optimization.
Cortisol and thyroid hormones must be in harmony for BHRT to work properly. We assess adrenal fatigue, cortisol rhythm, and thyroid function, then support them with adaptogens, glandular extracts, or bioidentical thyroid as needed. Balancing these systems helps reduce fatigue, brain fog, anxiety, and weight gain—common symptoms in women with midlife hormone imbalance.
If your liver isn’t clearing hormones well, you may experience estrogen dominance—even with “normal” levels. We support Phase 1 & 2 liver detox using sulforaphane, DIM, milk thistle, and methylated B vitamins. This reduces side effects like bloating or breast tenderness and helps you process hormones efficiently for better balance and mood stability.
Hormonal health thrives on lifestyle. We guide you through stress reduction techniques, movement strategies, and sleep support to enhance hormone function naturally. Meditation, acupuncture, strength training, and yoga can boost endorphins, reduce cortisol, and improve insulin sensitivity—all of which amplify the effectiveness of BHRT and improve your long-term well-being.
Hormonal balance improves ovulation, cycle regularity, uterine health, and emotional stability prior to conception or IVF.
We use bioidentical estrogen and testosterone pellets for long-term endocrine stability.
Optimizing gut health improves estrogen metabolism and hormone clearance.
We reduce xenoestrogen exposure and endocrine disruptors.
Hormone balance supports neurotransmitter function and emotional regulation.
Sarah, 48, came in with fatigue, irritability, poor libido, and disrupted sleep. Labs showed low estrogen, low testosterone, and high cortisol. We inserted estrogen/testosterone pellets, supported her adrenals with ashwagandha, and added IV magnesium and B vitamins. Within 6 weeks, Sarah reported better sleep, renewed sex drive, and stabilized mood. After 3 months, she felt like “herself” again—naturally.
Patient: Maria, 48, NYC
Symptoms: Hot flashes, fatigue, mood swings, low libido
Findings: Low estrogen, testosterone, high cortisol
Treatment:
• Estrogen + testosterone pellets
• Nutritional support
• Stress regulation
Results :
• Hot flashes resolved
• Energy restored
• Improved sleep
• Libido returned
• Mental clarity improved

Medical Director of Patients Medical

A holistic pain management physician

Consult Dr. Emine Cosar, MD. For Gynecology
Yes, when prescribed and monitored properly, pellets are a safe and effective hormone therapy used for over 70 years.
Most women need pellets every 3–6 months depending on metabolism and hormone levels.
The procedure is quick and performed under local anesthesia. Most women describe it as a mild pinch.
It is a form of hormone replacement that uses plant-derived hormones identical to those naturally produced by your body. Tiny pellets are inserted under the skin to release steady hormone levels over time.
Traditional HRT often uses synthetic hormones in pills or patches. Pellet therapy uses bioidentical hormones and provides consistent dosing without daily medication.
Most pellets last 3 to 5 months, depending on metabolism, activity level, and individual hormone needs.
The procedure is quick (about 10–15 minutes) and done with local anesthesia. Most patients feel only mild pressure or soreness for a day or two.
Many women notice improvements in 2–4 weeks, with full benefits developing over 6–8 weeks.
Pellets can support:
When prescribed and monitored by physicians, BHRT is considered safe and well-tolerated for most women. Ongoing lab testing ensures proper dosing.
No. In fact, balanced hormones often support metabolism and weight regulation. Weight gain usually comes from untreated hormonal imbalance.
Some women may experience temporary symptoms like breast tenderness or mild acne. These usually resolve as levels stabilize.
We use FDA-registered compounding pharmacies and test all batches for purity, sterility, and dosage accuracy.
We are out-of-network but provide superbills for partial reimbursement. Some labs may be covered.
Current evidence suggests bioidentical hormones may be safer than synthetic hormones, but every patient is evaluated individually for risk factors.
Yes. Pellet therapy is fully reversible. You can discontinue at any point in consultation with your doctor.
Yes. Patients Medical performs comprehensive hormone panels before starting and periodically during treatment.
Yes. Hormone balance strongly influences neurotransmitters like serotonin and dopamine, which affect mood and emotional stability.
No. It’s also used for:
Some consultation and testing may be covered, but pellet therapy itself is often considered elective. Our team provides transparent pricing.
Yes. Best results come from combining BHRT with:
Pellet therapy works best as part of a whole-person integrative plan.
Patients Medical specializes in gently helping the patient identify the root cause of their medical issues and then assist them to recover from their problems to help them move forward to good health.
To schedule an in person on Tele-medicine appointment, please call our office at (212) 794-8800 or email us at info@PatientsMedical.com We look forward to hearing from you
Patients Medical PC
1148 Fifth Avenue, Suite 1B New York, NY 10128
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