NYC’s Leading Integrative Health Care Center

Anti-Aging and Longevity Treatments Remember when you were in college and stayed up all night drinking beer, eating pizza, and partying; yet you still were able to attend class in the morning? How many of you could do that now?
You’ve been told your blood work is “normal,” yet something clearly isn’t right. The fatigue doesn’t go away. Your joints ache in different places each day. Brain fog makes it hard to focus, and you may even feel tingling, heart palpitations, or unexplained anxiety.
For many patients, these symptoms are dismissed, misdiagnosed, or treated in isolation. Lyme disease — especially chronic or late-stage Lyme — is one of the most commonly missed conditions in conventional medicine. Standard tests often fail to detect it, particularly if the infection is longstanding or if co-infections are involved.
At Patients Medical, we take a root-cause, integrative approach to Lyme disease testing in NYC, combining advanced diagnostics with a deeper understanding of immune function, inflammation, and hidden infections.
Rather than relying on a single screening test, we evaluate the full clinical picture, helping uncover what standard testing often misses.
Lyme disease testing is a group of diagnostic tools designed to detect infection with Borrelia burgdorferi and other tick-borne pathogens. These tests evaluate immune responses, antibodies, and markers of inflammation to determine whether an infection is present or ongoing.
Standard testing typically includes ELISA and Western Blot, which look for antibodies. However, advanced testing goes further — identifying chronic infection, immune suppression, and co-infections that may complicate diagnosis.
According to the CDC and peer-reviewed infectious disease research, standard two-tier testing may miss cases of chronic Lyme disease, especially in later stages.
At Patients Medical, we combine conventional and specialty tests to improve diagnostic accuracy and provide a clearer clinical picture.
When the body encounters bacteria like Borrelia, the immune system produces antibodies (IgM and IgG) to fight the infection. In a typical scenario, these antibodies are detectable in blood tests.
However, Lyme disease can disrupt this process. The bacteria may evade immune detection, suppress immune activity, or hide in tissues. This can lead to:
Many Lyme symptoms overlap with autoimmune, neurological, and hormonal conditions, which is why they are often misdiagnosed. Patients may be told they have stress, aging, or unrelated conditions.
Additionally, symptoms can come and go or shift throughout the body, making diagnosis even more challenging.
Lyme disease testing is especially important for individuals who continue to experience unexplained symptoms despite normal lab results. Many patients come to us after seeing multiple specialists without answers.
You may benefit from testing if you’ve had tick exposure, spend time outdoors, or live in regions where Lyme disease is prevalent. It’s also highly relevant for those diagnosed with chronic fatigue, fibromyalgia, autoimmune disorders, or neurological symptoms without a clear cause.
Even without a known tick bite, Lyme disease can still be present — making advanced testing critical for accurate diagnosis.
| Test | What It Measures | Best Used For | Sample Type | Turnaround Time |
| ELISA | Antibodies | Early detection | Blood | 3–5 days |
| Western Blot | Borrelia proteins | Confirmation | Blood | 5–7 days |
| IGeneX Panel | Multiple strains | Chronic Lyme | Blood | 10–14 days |
| CD57 | Immune cells | Chronic cases | Blood | 5–7 days |
| Co-Infection Panel | Tick infections | Complex symptoms | Blood | 7–10 days |
| ELISPOT | Immune activity | Active infection | Blood | 7–10 days |
| C3a/C4a | Inflammation | CIRS | Blood | 5–7 days |
A 42-year-old professional with 3 years of fatigue and joint pain had normal tests.
Advanced testing revealed chronic Lyme + Bartonella.
Treatment included IV therapy, herbal antimicrobials, and immune support.
Dr. Rashmi Gulati
Dr. Rashmi Gulati is the Medical Director of Patients Medical and one of New York City’s foremost integrative physicians. With over 30 years of clinical experience, she specialises in Lyme disease, chronic infections, immune dysfunction, and chronic fatigue, as well as hormone imbalance and thyroid disorders.
Lyme disease, co-infections, and immune dysfunction.
No. ELISA alone misses up to 50% of cases; we use ELISA + Western Blot and advanced IGenex options danielcameronmd.comstramcenter.com.
Acute relies on IgM, PCR, and symptoms. Chronic needs IgG, co-infections, and functional markers rupahealth.comrupahealth.com.
Through panel tests for Babesia, Bartonella, Ehrlichia, Anaplasma—often with IGenex or specialized labs rupahealth.comrupahealth.com.
Yes, particularly with untreated co-infections or without supportive healing—so we recommend proactive monitoring and immune support.
If you have fatigue, pain, or neurological symptoms.
Yes, integrative therapies are effective.
Only when active infection is confirmed. We may start herbal protocols first, or integrate antibiotics and support simultaneously.
Yes—symptom-adapted testing, especially if tick exposure or persistent symptoms are present.
Absolutely. Nutrient deficiencies (e.g., B vitamins, magnesium) can hinder healing and immune response off the Lyme bug rupahealth.comkaplanclinic.com.
We’re out-of-network but provide superbills—many labs and services are reimbursable.
Some experience relief in weeks; deeper neuro-immune recovery often takes 3–6 months or longer, especially in chronic cases.
Reviewed and authored by Dr. Rashmi Gulati, MD | Board-Certified Integrative Physician | Medical Director, Patients Medical | 30+ years of clinical experience
Don’t ignore persistent symptoms. Get answers with advanced testing.
Call: (212) 794-8800
Email: info@patientsmedical.com
Location: Midtown Manhattan
Patients Medical specializes in gently helping the patient identify the root cause of their medical issues and then assist them to recover from their problems to help them move forward to good health.
To schedule an in person on Tele-medicine appointment, please call our office at (212) 794-8800 or email us at info@PatientsMedical.com We look forward to hearing from you
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1148 Fifth Avenue, Suite 1B New York, NY 10128
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