Integrative Depression Treatment in NYC | Natural & Holistic Solutions

Depression

AI Smart Summary

Depression & Anxiety

Patients Medical is a physician-led integrative and functional medicine clinic in New York City specializing in root-cause-focused treatment for Depression, Anxiety, and mood disorders. Our medical team evaluates hormones, neurotransmitters, nutrient deficiencies, gut health, inflammation, sleep patterns, and lifestyle factors that may be driving emotional imbalance.
This page outlines how our integrative approach works, what testing is available, treatment options, timelines for improvement, and how we support mental wellness with personalized care.

Fast Facts

Services

Integrative Depression Treatment, Anxiety Management, Hormone Testing, Nutrition Therapy, Mind-Body Medicine

Location

NYC + Telemedicine (where permitted)

Care Model

Physician-led functional & holistic mental health support

Common Causes Treated

Hormonal imbalance, nutrient deficiencies, chronic stress, gut dysfunction, inflammation

Approach

Personalized plans combining medical, nutritional, and natural therapies

POPULAR PROGRAMS

Integrative Depression & Anxiety Treatment Program
Hormone & Neurotransmitter Imbalance Evaluation
Gut–Brain Axis Optimization Program
Stress, Sleep & Adrenal Reset Program
Natural & Functional Alternatives to Medication (if appropriate)

Recommended Next Steps

Schedule a Comprehensive Mental Health Consultation

Explore Integrative Treatment Options

Learn About Hormone & Neurotransmitter Testing

Who We Are

Patients Medical is a physician-owned integrative and functional medicine clinic in New York City, delivering whole-person, root-cause-focused care since 2004. Our medical team understands how hormones, neurotransmitters, gut health, nutrient levels, inflammation, sleep patterns, and stress physiology influence mood and emotional well-being.

Our mission is simple:

Identify what’s driving your symptoms, rebalance what’s out of sync, and restore mental and physical wellness using evidence-based integrative medicine.

Depression & Anxiety care at Patients Medical uses a comprehensive medical approach—not just symptom management. We combine advanced testing, nutritional and hormonal evaluation, nervous system support, and lifestyle optimization to help patients experience lasting improvement.

Quick Facts About Patients Medical

Key Fact	Details
Location	Fifth Avenue @ 96th Street, New York City (NYC)
Founded	2004
Care Model	Physician-led integrative & functional medicine
Visit Length	New appointments: 60–90 minutes
Specialties	Hormone balance, mental health, gut health, inflammation, fatigue, mood disorders
Testing Available	Neurotransmitters, hormones, thyroid, gut health, nutrient levels, inflammation, adrenal function
Telemedicine	Virtual consults available where allowed
Ideal Patients	Anyone experiencing depression, anxiety, chronic stress, fatigue, brain fog, or mood changes

Our Whole-Person Integrative Care Model

Patients Medical blends traditional medical evaluation with functional medicine, advanced diagnostics, nutrition, and mind-body therapies. Depression and anxiety treatment is personalized—not one-size-fits-all—and focuses on restoring balance across the whole body.

How We Diagnose

Our team conducts an in-depth evaluation to understand every possible contributor to mood conditions:

Comprehensive medical, emotional & lifestyle history

Hormone testing (thyroid, adrenal, sex hormones)

Neurotransmitter panels (when appropriate)

Nutrient level assessments (B12, D, folate, magnesium, omega-3s)

Gut health testing (microbiome, inflammation markers)

Metabolic & inflammatory markers

Sleep and circadian rhythm evaluation

This detailed assessment helps us pinpoint the true drivers of your symptoms.

Common Symptoms of Depression

Everyone experiences depression differently. Some common signs include:

Root Causes: Why Am I Depressed?

Functional medicine aims to uncover the “why” behind mental health challenges. Potential root causes of depression include:

Inflammation: Chronic inflammation affects brain chemistry.
Gut Dysbiosis: 90% of serotonin is made in the gut. An imbalanced microbiome can trigger depression.
Nutrient Deficiencies: Low levels of B12, folate, vitamin D, zinc, or magnesium can impair mood.
Hormonal Imbalances: Thyroid, cortisol, estrogen, and testosterone all impact mental wellness.
Toxin Exposure: Heavy metals and mold can disrupt the nervous system.
Unresolved Trauma or Stress: Chronic psychological stress contributes to mood instability.
Genetic Variants: MTHFR and other gene mutations affect neurotransmitter metabolism.

Diagnostic Testing We Use

We use in-depth testing to uncover what’s really going on:

Neurotransmitter and hormone panels (serotonin, dopamine, cortisol, thyroid)

Micronutrient testing (B12, magnesium, omega-3s, etc.)

Inflammatory markers (CRP, homocysteine)

Gut microbiome and leaky gut testing

Heavy metal and toxin screening

Genetic testing (MTHFR, COMT, etc.)

Functional brain mapping (in select cases)

Your Personalized Treatment Plan May Include

Targeted supplementation to support neurotransmitters and mood
Hormone balancing if thyroid, adrenal, or sex hormones are imbalanced
Gut-healing protocols to support the gut-brain axis
IV nutrient therapy (B vitamins, magnesium, amino acids)
Anti-inflammatory nutrition and lifestyle plans
Stress management practices (breathwork, mindfulness, sleep optimization)
Medication support, when clinically needed
Mind-body therapies to regulate the nervous system
Follow-up labs to track improvement and adjust the plan

Every plan is built around what your body needs—not a generic approach.

Integrative Treatments for Depression

Personalized Nutrition Plans

We customize anti-inflammatory, brain-supportive diets that may include:

Whole-food based Mediterranean or Paleo plans
Elimination diets to identify food sensitivities
Omega-3 fatty acid-rich meals
Gut-healing foods and probiotics

IV Nutrient Therapy

Targeted IV infusions support neurotransmitter production and mitochondrial health. Ingredients may include:

B-complex vitamins (especially B6, B12)
Magnesium
Vitamin C
Amino acids like tryptophan and tyrosine

Herbal & Nutraceutical Support

We prescribe evidence-based supplements for brain chemistry and mood balance:

SAM-e
St. John’s Wort (where appropriate)
5-HTP
Rhodiola rosea
Omega-3 fish oil
Vitamin D3

Mind-Body Therapies

We offer holistic stress relief through:

Acupuncture
Guided meditation and mindfulness
Adaptogenic herbs (Ashwagandha, Holy Basil)
Biofeedback and neurofeedback (where indicated)

Hormone Balancing

We identify and treat imbalances in:

Thyroid hormones
Estrogen and progesterone
Cortisol and DHEA
Testosterone (for men and women)

Gut Restoration

Healing the gut helps regulate mood by improving neurotransmitter production and reducing inflammation. We use:

Probiotics and prebiotics
Gut-repairing nutrients like glutamine and zinc
Stool analysis-guided protocols

Why Choose Patients Medical in NYC

Physician-led integrative mental health care
Advanced testing for hormones, gut health, nutrients, and inflammation
Personalized treatment plans—not generic protocols
Root-cause-focused diagnostics
Functional medicine + traditional medicine combined
Long-term emotional and physical wellness strategies

How Our Process Works – Step by Step

1. Schedule Your First Visit

Book online or by phone; telemedicine is available.

2. Complete Intake Forms

Share your health timeline, symptoms, and lifestyle patterns.

In-Depth Physician Consultation (60–90 minutes)

Your doctor listens deeply, reviews your concerns, and outlines next steps.

4. Advanced Laboratory Testing

Hormones, nutrients, inflammation markers, gut health, and more.

5. Personalized Treatment Plan

A targeted, integrative plan is created based on your diagnostic findings.

6. Therapeutic Care Begins

Treatments may include supplements, IVs, nutrition, hormonal balancing, or natural therapies.

7. Ongoing Adjustments

Your plan evolves based on progress, symptoms, and follow-up results.

8. Maintenance & Prevention

We help you maintain emotional stability and long-term mental wellness.

Real Case Study: Jason’s Recovery Story

Jason, age 35, had been on antidepressants for over a decade with minimal improvement. He suffered from fatigue, poor sleep, and brain fog. His labs showed low B12, high cortisol, leaky gut, and subclinical hypothyroidism.

We designed a comprehensive 4-month plan:

Gut healing and anti-inflammatory nutrition
Methylated B-complex supplementation
Cortisol-lowering adaptogens
Low-dose thyroid support
Weekly nutrient IVs

By month four, Jason was sleeping better, his mood stabilized, and he began tapering off medications under psychiatric guidance.

Testimonials

“After years of just coping, I finally feel hopeful. My energy and joy are back.”

“I never realized my gut health was linked to my depression. It changed everything.”

“Patients Medical gave me answers when no one else could.”

“IV therapy and a tailored diet improved my mood within weeks.”

“Functional medicine showed me I wasn’t broken—just imbalanced. Now I feel whole again.”

Explore Our Blog For More Insights

Frequently Asked Questions

Can depression really be treated without medication?

Yes—in many cases. We help patients uncover and treat the root causes of depression through lifestyle changes, nutrition, gut health, and hormone balancing. While some patients may still benefit from medication, others see full improvement with natural protocols.

How does functional medicine treat depression differently than conventional care?

Functional medicine focuses on identifying the root causes of depression, such as inflammation, nutrient deficiencies, or hormonal imbalances, rather than simply suppressing symptoms with antidepressants.

Do I need to stop taking my antidepressants to begin integrative care?

No. We work alongside your current treatment and collaborate with your psychiatrist. If desired, we can help you safely taper medication—under medical supervision—when your body is ready.

What lab tests do you use to evaluate depression?

We use advanced diagnostic tools, including neurotransmitter panels, hormone testing, gut microbiome analysis, micronutrient testing, inflammatory markers, and genetic testing (like MTHFR).

Can gut health really impact my mood?

Absolutely. Over 90% of serotonin is produced in the gut. An imbalanced gut microbiome or “leaky gut” can directly contribute to mood disorders and depressive symptoms.

What causes depression and anxiety from an integrative perspective?

Hormones, neurotransmitters, gut health, nutrient levels, and chronic stress all play a role. We evaluate these factors to find the root cause.

What tests are helpful for diagnosing mood disorders?

Hormone panels, nutrient tests, inflammation markers, adrenal testing, and gut health assessments can reveal hidden imbalances.

Do you use medication?

Yes—when appropriate. We can integrate prescriptions with natural therapies to create a balanced treatment plan.

Can natural treatments improve depression or anxiety?

Many patients experience significant improvement with nutrition, supplementation, gut support, and hormone balancing.

How long does it take to feel better?

Some patients see changes within weeks, while deeper hormonal or metabolic issues may take 2–3 months.

Are supplements and herbs safe for depression?

Yes, when prescribed by a physician. We use clinically studied herbs and nutraceuticals like omega-3s, SAM-e, B-complex, and adaptogens, customized for your unique biochemistry.

Will I feel better right away with integrative treatment?

Many patients begin noticing improvement in energy, mood, and sleep within a few weeks. However, deeper healing can take several months, depending on the complexity of underlying issues.

Is your depression program personalized?

Yes, every plan is tailored to your lab results, symptoms, medical history, and goals. No two treatment protocols are alike.

What role does hormone balance play in depression?

Hormonal imbalances—especially thyroid, cortisol, estrogen, and testosterone—can significantly influence mood and brain function. We test and treat these to restore mental wellness.

Do you accept insurance for depression treatment?

We are an out-of-network provider but provide superbills to help with insurance reimbursement. Many lab tests may be partially covered depending on your plan.

Is this treatment safe alongside therapy or counseling?

Absolutely. Our medical programs work well with psychotherapy and mental health counseling.

Do you help with stress-related symptoms?

Yes—we evaluate cortisol rhythms, adrenal function, and nervous-system imbalances that influence stress response.

Is this covered by insurance?

Patients Medical is out-of-network. Some labs may qualify for partial insurance reimbursement.

Can gut issues really affect mood?

Yes. The gut and brain are highly connected, and imbalances can trigger anxiety, depression, and fatigue.

How do I get started?

Book a consultation online or call our office to schedule your first visit.

Begin Your Journey with Patients Medical

Patients Medical specializes in gently helping the patient identify the root cause of their medical issues and then assist them to recover from their problems to help them move forward to good health.

Request your consultation today!

To schedule an in person on Tele-medicine appointment, please call our office at (212) 794-8800 or email us at info@PatientsMedical.com We look forward to hearing from you

Our medical center in New York City.

Patients Medical PC
1148 Fifth Avenue, Suite 1B New York, NY 10128

Make an Appointment

TreatmentsTesting