Sjögren’s Syndrome – Symptoms, Causes, Natural Conditions & Integrative Solutions

Introduction: Why Sjögren’s Syndrome Needs a New Approach

Sjögren’s Syndrome is an autoimmune condition that silently disrupts your daily life—causing dry eyes, dry mouth, fatigue, and joint pain. At Patients Medical in New York City, we take a comprehensive, integrative medicine approach to treating Sjögren’s. We look beyond symptom relief to uncover and address the underlying immune imbalances, gut issues, hormonal shifts, and environmental triggers driving the condition.
We treat the root causes, not just the dryness.

What Is Sjögren’s Syndrome?

Sjögren’s Syndrome is a chronic autoimmune disease in which the immune system mistakenly attacks the glands that produce moisture in the eyes, mouth, and other parts of the body. While it often occurs alongside other autoimmune conditions like rheumatoid arthritis or lupus, it can also present independently.

Types of Sjögren’s:
  • Primary Sjögren’s: Occurs on its own without another autoimmune disorder.
  • Secondary Sjögren’s: Develops in connection with other autoimmune diseases such as RA or lupus.

Common Symptoms of Sjögren’s Syndrome

Sjögren’s symptoms can range from mild to debilitating, and many go undiagnosed for years. Signs to watch for include:

If you’re experiencing these symptoms, especially in combination, testing is recommended.

Root Causes: Why Did You Develop Sjögren’s Syndrome?

Functional medicine seeks to understand why the immune system has gone off course. In Sjögren’s Syndrome, these factors often play a role:

  • Gut Dysbiosis & Leaky Gut: Disrupted intestinal barriers allow inflammatory triggers into the bloodstream.
  • Hormonal Imbalance: Estrogen and cortisol imbalances can impact immune regulation.
  • Viral Infections: Epstein-Barr virus (EBV) and CMV may trigger or worsen autoimmune activity.
  • Toxic Burden: Mold exposure, heavy metals, or environmental toxins can overstimulate immune function.
  • Food Sensitivities: Gluten, dairy, and nightshades may trigger flares.
  • Chronic Stress: Affects adrenal health and immune modulation.
  • Mitochondrial Dysfunction: Impacts energy levels and immune system resilience.

Diagnostic Testing We Use

At Patients Medical, we use in-depth diagnostic panels to uncover what’s driving your autoimmunity:

Autoimmune panels (ANA, SSA/Ro, SSB/La antibodies)

Salivary gland and tear production tests (Schirmer’s test)

Gut health analysis (microbiome, leaky gut markers)

Viral load testing (EBV, CMV)

Heavy metal and mycotoxin screening

Hormone panels (estrogen, cortisol, thyroid)

Inflammatory markers (CRP, ESR, homocysteine)

Nutritional deficiencies (Vitamin D, Omega-3s, B12)

Integrative Treatments for Sjögren’s Syndrome

Nutritional Therapy

We develop anti-inflammatory, autoimmune-calming diets tailored to your triggers and metabolism:

  • Gluten-free, dairy-free, or autoimmune protocol (AIP) diets
  • Gut-healing nutrition to restore barrier function
  • High-antioxidant foods to reduce oxidative stress
  • Hydrating foods and teas to support moisture production

Herbal & Nutraceuticals

Our physicians may recommend targeted supplements, including:

  • Omega-3 fatty acids – For joint and eye lubrication
  • Curcumin – A potent anti-inflammatory
  • Vitamin D3 – Regulates immune function
  • Quercetin & Resveratrol – Natural mast cell stabilizers
  • Licorice root, marshmallow root – To support mucosal membranes

All supplements are medically dosed and monitored.

Stress Reduction

We integrate therapies like:

  • Acupuncture
  • Guided meditation and breathwork
  • Adaptogenic herbs like ashwagandha and holy basil
  • Vagal nerve stimulation techniques

Hormone Balancing

We assess and optimize adrenal, thyroid, and sex hormones to support immune function and reduce symptom severity.

Gut Repair & Detox

We use a 5R gut-healing approach (Remove, Replace, Reinoculate, Repair, Rebalance) and targeted detoxification to address leaky gut and reduce autoimmune flare-ups.

IV Vitamin Therapy

Custom infusions with Vitamin C, glutathione, B12, and magnesium help reduce fatigue, lower inflammation, and support immune balance.

Real Case Study: Evelyn’s Path to Relief

Evelyn, a 56-year-old woman, came to us with years of dry mouth, red eyes, and fatigue. She had been on immunosuppressants but still felt depleted.
Our testing revealed:

  • Elevated anti-SSA antibodies
  • Low cortisol and estrogen
  • Leaky gut and low beneficial gut flora
  • Past EBV reactivation

We designed a 16-week integrative care plan:

  • Gut-healing protocol with glutamine, probiotics, and AIP diet
  • IV vitamin therapy twice monthly
  • Hormone balancing with bioidentical estrogen and adrenal support herbs
  • Anti-viral and antioxidant herbal protocol

Four months later, Evelyn’s energy improved significantly, her dry mouth lessened, and her inflammatory markers dropped dramatically. She reduced her medications under her rheumatologist’s supervision.

Testimonials

Frequently Asked Questions

While not fully curable, symptoms and flares can be significantly reduced and sometimes put into remission with root-cause integrative care.

Primary occurs on its own. Secondary is associated with other autoimmune diseases like lupus or rheumatoid arthritis.

Yes, we provide natural and functional medicine approaches that may reduce reliance on conventional drugs under supervision.

No—fatigue, joint pain, dry skin, and hormonal symptoms are also common and treatable.

Absolutely. Many patients see symptom improvement by eliminating inflammatory foods and healing the gut.

Hormonal shifts—especially in estrogen and cortisol—can worsen autoimmunity and dryness symptoms.

Yes. Chronic stress dysregulates the immune system. Managing it is key to controlling flares.

Yes. We customize all protocols for age, medications, and comorbidities.

We are out-of-network but provide superbills for reimbursement. Labs may be partially covered.

Some notice improvement within weeks, while deeper healing often takes 2–4 months.

Begin Your Journey with Patients Medical

Patients Medical specializes in gently helping the patient identify the root cause of their medical issues and then assist them to recover from their problems to help them move forward to good health.

Request your consultation today!

To schedule an in person on Tele-medicine appointment, please call our office at (212) 794-8800 or email us at info@PatientsMedical.com We look forward to hearing from you

Our medical center in New York City.

Patients Medical PC
1148 Fifth Avenue, Suite 1B New York, NY 10128

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