What causes restless leg syndrome?

What causes restless leg syndrome?

Introduction: Why RLS Needs a New Approach

Restless Leg Syndrome (RLS) is a neurological condition that causes an uncontrollable urge to move your legs, often accompanied by discomfort, especially at night. While conventional treatments focus on managing symptoms, at Patients Medical in New York City, we go beyond symptom management. Our integrative approach combines conventional, holistic, and functional medicine to understand the root causes of your RLS and provide personalized, natural solutions to help you regain restful sleep and enhance your quality of life.

We treat the whole person—not just the legs.

What Is Restless Leg Syndrome (RLS)?

RLS is a disorder that affects the nervous system, creating uncomfortable sensations in the legs and an irresistible urge to move them, typically during periods of inactivity or when lying down. These sensations are often described as crawling, tingling, pulling, or itching. Symptoms tend to worsen in the evening and can interfere with sleep, leading to fatigue and a diminished quality of life.

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Common Symptoms of RLS

Root Causes: Why Did You Develop RLS?

Functional medicine helps uncover the root causes of Restless Leg Syndrome, which may be connected to various underlying factors, including deficiencies, imbalances, and lifestyle factors. Some of the common root causes include:

  • Iron Deficiency: Low iron levels, particularly in the brain, have been linked to RLS. Iron is crucial for dopamine production, a neurotransmitter involved in motor control.
  • Dopamine Imbalance: Dysfunction in dopamine production or receptor activity in the brain may contribute to the symptoms of RLS.
  • Chronic Inflammation: Inflammation in the nervous system or body may contribute to nerve dysfunction and worsen RLS symptoms.
  • Nutrient Deficiencies: Deficiencies in essential vitamins and minerals, including magnesium, folate, and B vitamins, can trigger or intensify RLS symptoms.
  • Peripheral Neuropathy: Nerve damage caused by conditions such as diabetes or alcoholism can lead to sensations of restlessness in the legs.
  • Sleep Disorders: Poor sleep quality or untreated sleep apnea can exacerbate RLS symptoms.
  • Pregnancy: Hormonal changes during pregnancy, particularly in the third trimester, can contribute to the development or worsening of RLS.

Medications: Some medications, including antihistamines and antidepressants, can trigger RLS or worsen existing symptoms.

Diagnostic Testing We Use

At Patients Medical, we use advanced diagnostic testing to understand what’s driving your RLS and personalize your treatment plan. These tests may include:

Iron levels (serum ferritin and transferrin saturation) to assess iron deficiency

Dopamine and neurotransmitter testing to evaluate brain function

Magnesium and B-vitamin levels (magnesium, B12, folate) to identify deficiencies

Comprehensive sleep studies to rule out sleep disorders like sleep apnea

Peripheral neuropathy testing (nerve conduction studies) for signs of nerve damage

C-reactive protein (CRP) and other inflammatory markers to assess inflammation levels

Thyroid function tests to ensure proper metabolic balance

Integrative Treatments for RLS

Hormonal Balancing

For individuals with RLS that worsen during pregnancy or other hormonal fluctuations, we address hormone imbalances with natural therapies such as:

  • Bioidentical hormone replacement for perimenopausal and menopausal women
  • Progesterone therapy to balance hormonal fluctuations during pregnancy

Stress Reduction

Since stress can exacerbate RLS symptoms, we incorporate therapies designed to promote relaxation and reduce anxiety:

  • Mindfulness meditation and relaxation techniques to calm the mind and reduce nervous system overactivity
  • Acupuncture to balance energy, promote blood flow, and calm nerve function
  • Yoga and Tai Chi to stretch and relax muscles, promoting better circulation

Sleep Optimization

As sleep disruption is common with RLS, improving sleep hygiene and addressing underlying sleep disorders are key components of treatment. We offer:

  • Cognitive Behavioral Therapy for Insomnia (CBT-I) to help with insomnia related to RLS
  • Sleep apnea treatment (if diagnosed) with CPAP therapy or other appropriate interventions
  • Melatonin supplementation to regulate sleep-wake cycles and promote restful sleep

Herbal & Nutraceuticals

Several herbal remedies and supplements have been shown to support dopamine production, reduce inflammation, and ease RLS symptoms. Common recommendations include:

  • Iron supplements (in cases of iron deficiency)
  • Magnesium supplements for muscle relaxation
  • Valerian root (known to calm the nervous system)
  • L-Theanine (amino acid that promotes relaxation and sleep)
  • Vitamin D3 for overall health and inflammation regulation
  • Turmeric and ginger for their anti-inflammatory effects

All supplements are dosed and monitored by a physician to ensure safety and effectiveness.

Nutritional Therapy

A personalized nutritional plan can help alleviate the symptoms of RLS by addressing nutrient deficiencies and improving nerve function. Recommended dietary adjustments include:

  • Iron-rich foods such as red meat, leafy greens, beans, and fortified cereals
  • Magnesium-rich foods like nuts, seeds, spinach, and bananas to relax muscles and nerves
  • B vitamins (B12, folate) to support nerve health and brain function
  • Anti-inflammatory foods such as turmeric, ginger, and omega-3 fatty acids to reduce systemic inflammation

Real Case Study: Mark’s Journey to Relief

Mark, age 47, came to us with worsening Restless Leg Syndrome, especially at night, which severely disrupted his sleep. He reported feeling “crawling” sensations in his legs that worsened after a long day at work. After extensive testing, we discovered that Mark had low iron levels and magnesium deficiency.

We developed a personalized plan for Mark, which included:

  • Iron supplements to improve his iron levels and support dopamine production
  • Magnesium and B vitamins to promote muscle relaxation and nerve health
  • Relaxation techniques including guided meditation and acupuncture for stress relief
  • Sleep hygiene improvement to promote better quality rest

After two months, Mark reported a dramatic improvement in his RLS symptoms. His sleep quality improved significantly, and he felt more energized during the day.

Real Case Study: Mark’s Journey to Relief

Testimonials

Frequently Asked Questions

RLS can be caused by iron deficiency, dopamine imbalance, peripheral neuropathy, and other factors such as stress and poor sleep.

Yes, RLS is a neurological disorder that affects the nervous system, causing an uncontrollable urge to move the legs due to uncomfortable sensations.

RLS is characterized by the urge to move the legs, especially at night, accompanied by uncomfortable sensations like crawling or tingling.

Yes, chronic stress can trigger or exacerbate RLS symptoms by overstimulating the nervous system and increasing cortisol levels.

Yes, RLS can be managed with natural remedies such as iron supplementation, magnesium, relaxation techniques, and acupuncture.

The duration of treatment depends on the underlying causes, but many patients experience improvement within a few weeks of starting treatment.

Yes, RLS can be linked to conditions such as diabetes, pregnancy, iron deficiency, and peripheral neuropathy.

Yes, low iron levels are a common cause of RLS, particularly in the brain, where iron is essential for dopamine production.

RLS may not be fully preventable, but managing stress, improving sleep quality, and addressing nutritional deficiencies can reduce symptoms.

Yes, we offer iron testing to determine if iron deficiency is contributing to your RLS symptoms.

Begin Your Journey with Patients Medical

Patients Medical specializes in gently helping the patient identify the root cause of their medical issues and then assist them to recover from their problems to help them move forward to good health.

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To schedule an in person on Tele-medicine appointment, please call our office at (212) 794-8800 or email us at info@PatientsMedical.com We look forward to hearing from you

Our medical center in New York City.

Patients Medical PC
1148 Fifth Avenue, Suite 1B New York, NY 10128

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