What is Sjogren’s Syndrome?

Why Sjogren’s Syndrome Needs a New Approach

Sjogren’s Syndrome is a chronic autoimmune condition that causes dry eyes, dry mouth, fatigue, and often goes undiagnosed for years. Conventional treatment typically focuses on symptom management, but does little to explore why the immune system is attacking healthy glands in the first place.

At Patients Medical in New York City, we take a functional medicine approach. We search for and address the root causes—such as gut imbalances, nutrient deficiencies, chronic infections, and environmental triggers. Through integrative care, we aim not only to ease symptoms but to rebalance the immune system naturally and restore your quality of life.

What Is Sjogren’s Syndrome?

Sjogren’s Syndrome is an autoimmune disease in which the body’s immune system mistakenly attacks moisture-producing glands, especially those in the eyes and mouth. It may occur alone (primary Sjogren’s) or alongside other autoimmune diseases like rheumatoid arthritis or lupus (secondary Sjogren’s).

Commonly Affected Glands and Systems:
  • Salivary glands
  • Lacrimal (tear) glands
  • Joints
  • Skin
  • Lungs, kidneys, and nervous system (in more severe cases)

Common Symptoms of Sjogren’s Syndrome

Because it affects multiple body systems, symptoms can be widespread and include:

Root Causes: Why Did You Develop Sjogren’s Syndrome?

Autoimmune diseases like Sjogren’s are rarely caused by a single factor. Our integrative team explores why your immune system has gone rogue.

Functional Medicine Looks at These Underlying Triggers:
  • Leaky gut syndrome (intestinal permeability)
  • Chronic infections (Epstein-Barr virus, H. pylori, Candida)
  • Food sensitivities (gluten, dairy, corn)
  • Hormonal imbalances (especially estrogen and cortisol)
  • Toxin accumulation (mercury, BPA, mold exposure)
  • Genetic predispositions activated by environmental stressors
  • Stress and adrenal fatigue
  • Mitochondrial dysfunction
  • Poor detoxification pathways (MTHFR gene variants)

By identifying and treating the root drivers of inflammation, we can help regulate the immune response and improve glandular function.

Diagnostic Testing We Use

We go beyond traditional labs to uncover the deeper drivers of autoimmune activity and inflammation:

Autoantibody panels (ANA, SS-A/Ro, SS-B/La)

Inflammatory Markers (ESR, CRP, cytokines)

Hormone testing (thyroid, adrenal, estrogen, progesterone)

Gut health testing (microbiome, leaky gut, candida, parasites)

Nutritional assessments (vitamin D, B12, omega-3s, zinc, magnesium)

Food sensitivity and allergy panels

Heavy metal and environmental toxin screening

Epstein-Barr virus and stealth infection panels

Genetic testing (MTHFR, detox genes)

Integrative Sjögren’s Treatments

Mucosal Restoration Therapies

  • Autologous serum eye drops (from patient’s blood)
  • Pro-biotic oral rinses (for oral microbiome balance)
  • Hyaluronic acid supplements (for moisture retention)

Immune Modulation

  • Low-dose naltrexone (LDN) (reduces inflammation)
  • IVIG therapy (for severe cases)
  • Peptide therapy (Thymosin alpha-1)

Gut-Immune Repair

  • Leaky gut protocols (glutamine, zinc carnosine)
  • Microbiome restoration (specific probiotic strains)
  • Autoimmune diet plans (AIP protocol)

Advanced Dryness Solutions

  • Lipiflow for meibomian glands
  • Electrostimulation for saliva production
  • Cevimeline alternatives (herbal secretagogues)

Systemic Support

  • IV hydration + nutrient therapy
  • Mitochondrial support (CoQ10, NAD+)
  • Neuropathy prevention (alpha-lipoic acid IVs)

Real Case Study: Elaine’s Return to Vitality

Elaine, age 46, was diagnosed with Sjogren’s after years of dry mouth, fatigue, and joint pain. She was on multiple medications but still felt drained and foggy.

At Patients Medical, we identified:

  • Low vitamin D and omega-3 levels
  • Elevated EBV antibodies
  • Leaky gut and multiple food sensitivities
  • High cortisol and estrogen dominance

Her 4-month plan included:

  • Autoimmune paleo diet and gut repair protocol
  • IV vitamin therapy with glutathione and B12
  • Acupuncture and adaptogenic herbs for adrenal balance
  • Hormone balancing with bioidentical progesterone
    By month 4, her dry mouth improved by 70%, her energy was back, and her joint pain had nearly vanished.

Testimonials

Frequently Asked Questions

 There is no conventional cure, but functional medicine can help put symptoms into remission by healing the root causes.

Yes. Anti-inflammatory and elimination diets can dramatically reduce symptom severity and flare frequency.

 Not always. Many patients reduce or avoid medications by following a comprehensive, integrative healing plan.

 Over 70% of the immune system resides in the gut. Healing the gut often calms autoimmune attacks.

 Yes. It can impact joints, skin, lungs, kidneys, nerves, and even blood vessels.

 Hormones like estrogen and cortisol play key roles in immune regulation. Imbalance can trigger or worsen autoimmunity.

Yes. Nutrients like omega-3s, hydration therapy, mucilaginous herbs, and acupuncture can help.

 Chronic stress increases inflammation and can trigger flare-ups. Managing stress is critical to healing.

 Absolutely. We often collaborate with your rheumatologist or primary doctor to ensure coordinated care.

 We are an out-of-network provider, but we offer superbills for reimbursement. Many advanced lab tests may be partially covered.

Begin Your Journey with Patients Medical

Patients Medical specializes in gently helping the patient identify the root cause of their medical issues and then assist them to recover from their problems to help them move forward to good health.

Request your consultation today!

To schedule an in person on Tele-medicine appointment, please call our office at (212) 794-8800 or email us at info@PatientsMedical.com We look forward to hearing from you

Our medical center in New York City.

Patients Medical PC
1148 Fifth Avenue, Suite 1B New York, NY 10128

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